Innate Immunity | Adaptive Immunity |
Is mediated by what cells? | |
What do they recognize? | |
How are the receptors encoded? | |
Why can’t they control all infections alone? | |
What do they do in response to antigen? |
Innate Immunity | Adaptive Immunity | |
Is mediated by what cells? | Macrophages, NK cells, neutrophils, mast cells eosinophils | T cells and B cells |
What do they recognize? | Pathogen patterns | Specific epitopes |
How are the receptors encoded? | Germline | Rearranged gene segments |
Why can’t they control all infections alone? | Pathogens evolve escape mechanisms | Takes too long to develop |
What do they do in response to antigen? | Engulf and destroy, induce inflammation | Produce antibodies, kill infected cells |